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Alpha Stim and Depression

Alpha-Stim electrotherapy works on psychiatric disorders, such as depression, by producing alterations in electric activity in large-scale brain networks. Research suggests that Alpha-Stim® CES modulates large-scale brain network activity patterns in two synergistic ways: by stimulating cranial nerves including the vagus nerve, and directly modulating oscillations in the temporal lobe which is part of the default mode network. In clinical trials, Alpha-Stim 82% of recipients reported a decrease of ≥ 50% or greater in depression scores after five weeks using the CES therapy.

Improve Overall Function

  • Reduces depression when co-morbid with anxiety
  • Reduces anxiety
  • Improves sleep quality and duration
  • Safe with no adverse effects
  • Enhances response to other therapies like tDCS, NFB, and HBOT

REFERENCE

  1. Barclay TH, Barclay RD. A clinical Trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014; 164:171-177. Presented at the American Psychological Association National Conference, Honolulu, July 2013.
  2. Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression. JJ Psych Behav Sci. 2019; 6(1): 25-31.

Study: First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression

Background: This study was designed to investigate the effectiveness of Alpha-Stim® cranial electrotherapy stimulation (CES) in a group of 86 first responders for the treatment of anxiety, insomnia, depression, and pain.

Methods: The study included a nonrandomized pretest-posttest design with participants choosing to participate or not (i.e., self-selecting into participation). The independent (treatment) variable in this study was exposure to active CES. Participants were instructed to use the Alpha-Stim at a comfortable current intensity level adjustable from 100-600 microamperes for 20-60 minutes daily. At pretest (baseline) and posttest, data on outcome measures included perceived level of discomfort specific to the following indications anxiety, insomnia, depression, and pain.

Results: Analysis of the results was done by measuring the differences between the pretest and posttest mean of the participants. For anxiety the pretest mean was 4.18 and the posttest was 1.93 producing a reduction in anxiety of 54% with p <.001, and Cohen effect size d=1.21 (large). Similar results were seen in insomnia with a pretest mean of 5.70 and posttest mean of 3.80 for a reduction of 33% with p<.001 (two-tailed), and effect size d=1.18 (large), depression measures were a pretest mean of 3.95 and posttest mean of 2.83 for a reduction of 28% with p <.001 (two-tailed), and effect size d=.81 (large) and the pain pretest mean was 4.62 and posttest mean of 2.58 for a reduction of 44% with p<.001, and effect size d=.72 (large).

Conclusions: These 86 police officers, sheriff’s officers, and firefighters experienced a very significant decrease in anxiety, insomnia, depression, and pain by using Alpha-Stim CES. The statistical analyses revealed highly significant values of p<.001 for anxiety, depression, insomnia, and pain. The effect size Cohen’s d values were large for all outcome measures indicating a high level of practical change from baseline to posttest, which supports the capability of Alpha-Stim CES technology in reducing anxiety, insomnia, depression and pain symptoms and the ability to monitor progress on the Alpha-Stim app. No complaints were made by participants except mild dizziness that resolved during a session when the current was adjusted down to a lower level. This study supported the hypothesis that the use of a smartphone application could be useful in helping individuals track their response to Alpha-Stim CES and in monitoring their progress over time.

 

REFERENCES

  1. Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression. JJ Psych Behav Sci. 2019; 6(1): 25-31.